Care and Conservation of Manuscripts is based on a series of seminars held at the University of Copenhagen.

The first seminar on the care and conservation of manuscripts took place in April 1994 at the University of Copenhagen and was organised by Gillian Fellows-Jensen from the Arnamagnæan Commission and Peter Springborg from the Arnamagnæan Institute, with the support of the Royal Library.

The seminar was modelled on a series of more informal meetings held by the "Research group on manuscript evidence" based at the Parker Library, Corpus Christi College, Cambridge, where a relatively small group of scholars, librarians and conservators met to discuss manuscripts from as many different points of view as possible in order to better understand the manuscripts as historical artifacts.

From the 13th - 15th April, 2016, the sixteenth seminar on the care and conservation of manuscripts were held at the University of Copenhagen, organized by Matthew James Driscoll. The seminar attracted over 200 participants with over 45 presentations held.